The topic will be the structure-function relationship in enzymes, in the specific case of [FeFe]-hydrogenase. Protein will be purified and crystallised which will then be photochemically activated and subsequently characterised spectroscopically and via (time-resolved) X-ray crystallography. Further details on the PhD programme can be found under this link.

The objectives of the project are to develop new lanthano-peptides catalysts with a well-folded peptide scaffold, high affinity for Ln(III) and positive interactions for substrate binding. The project will include peptide design and synthesis, characterisations using advanved analytical techniques (paramagnetic NMR, time-resolved luminescence) and molecular modelling, as well as evaluation of Ln-peptide catalysts on model reactions. Web: https://hureaulab.wixsite.com/equipeflcc

The project’s aim is to elaborate a luminescent Cu(II)-sensor, that is able to measure specifically labile/exchangeable Cu(II)-concentrations in biological systems, from simpler cell culture medium to the challenging blood plasma. Such a Cu(II)-sensor would be very useful as a tool to understand the Cu metabolism and might have applications for diagnosis of diseases with increased exchangeable Cu pool concentrations such as Wilson’s or Alzheimer’s disease. The project incolves a consortium with several collaborators from different disciplines, including group from the …

[Expired] Postdoc Position (2 years) in Bio/Medicinal Inorganic Chemistry in Strasbourg on “Luminescent Sensor to Detect the Labile Cu(II)-Pool, a Diagnostic Parameter for Wilson’s and Alzheimer’s diseasethe project” Read more »

This Ph.D. is financed by an ANR project (Bioinspired Oxidation of Methane). It will be pursued at the Institute of Molecular Sciences of Marseille, and will focus on the development of new caged catalysts based on Fe- or Cu- complexes. These structures will strongly enhance the catalytic efficiency of this challenging reaction, while keeping an excellent selectivity.

The aim of this project, emerged within the L2CM laboratory, is to develop a novel approach utilizing optical imaging to track the biotransformations of metal-based drug candidates in view of rationalizing their further pharmacomodulation. This will allow to establish a relationship between metal’s coordination sphere, metal-ligand interaction, and the complexes’ biotransformations to rationalize drug design. Web: http://www.l2cm.univ-lorraine.fr/l2cm/

Join LEM to develop catalytic systems for electrocatalytic oxidation of various organic substrates, using O2 and earth abundant metal complexes. You will thoroughly study the catalytic activities of selected Fe an Mn complexes and quantify and optimize their performances (efficiency and selectivity) using complementary synthetic, spectroscopic and electrochemical tools.

 Join us in determining the mechanisms of catalysis by metalloenzymes through the development and implementation of electron-nuclear double resonance (ENDOR) spectroscopy: The ENDOR and DFT characterization of key trapped catalytic and photogenerated intermediates  reveals mechanism, with synthetic biomimetic complexes providing key constraints!

There is an opening for a PhD position in the BiosCiences team on the desing of supported catalysts for hydrogen production. For further details, please see attachment and contact me at

There is an opening for a PhD position in the BiosCiences team on the computational investigation of molecular catalysts for hydrogen production. For further details, please see attachment and contact me at

Offre d’emploi : CDD de 12 mois au BIAM (Biology and Biotechnology Institute Aix-Marseille) au CEA de Cadarache, Equipe Interactions Protéine – Métal (https://biam.cea.fr/drf/biam) Profil souhaité : BTS en biochimie – biotechnologie Date prévisible de recrutement : octobre 2021 (sous réserve de l’accomplissement des formalités administratives)

Research in the Laboratory of Chemistry and Biology of Metals (CBM, Grenoble, France. https://www.cbm-lab.fr/en) focuses on the study of the structure, activity and regulation of complex biological systems that transport and use metal ions, and on the development of bio-inspired systems for applications in health, the environment and energy. The size of the Laboratory and the coherence of its research make it unique at both the national and international levels.

The pluri-disciplinary project, developed by a collaboration between two teams of the Lab BEE and BioCE, deals with in cristallo biocatalysis for a sustainable chemistry is still open. Our strategy for catalysis consists in the use of crystals of metalloenzymes to perform cascade reactions, that will impact the organic synthesis and the mode of drug synthesis.

The project involves structure determination of novel metalloenzymes by X-ray crystallography, with a focus on enzymes catalyzing peptides (RiPPs) post-translational modifications. Our goal is to decipher the mechanism and mode of interactions between these enzymes and their substrate.

Lieu : Laboratoire SPCMIB (Laboratoire de Synthèse et Physico-Chimie de Molécules d’Intérêt Biologique), CNRS UMR 5068, Univ. Toulouse III Paul Sabatier Objet : Le groupe SOMAB (Sondes Organo-Metalliques pour des Applications Biomédicales) du SPCMIB recherche un(e) jeune chercheur(se) ayant un profil polyvalent de synthèse et de spectroscopie/photophysique, en vue d’une candidature pour un poste de CR CNRS.

A post-doctoral position in structural biology is available at the ChemSyBio team (Paris-Saclay University, INRAE, Micalis) headed by Dr Olivier Berteau. The project involves structure determination of novel metalloenzymes catalyzing post-translational modifications in peptides (ribosomally synthesized and post-translationally modified peptides, RiPPs) in order to decipher their mechanisms and enzyme substrate interactions.

The Department of Chemistry and Applied Biosciences (www.chab.ethz.ch) at ETH Zurich and its Laboratory of Inorganic Chemistry (LAC) (www.lac.ethz.ch) invite applications for the above-​mentioned position. The research activities at the LAC encompass synthesis of inorganic compounds on the molecular and nanometre scale, extended solids, and characterisation of complex reaction systems with high resolution methods at the atomic and molecular levels.

Biomimetic inorganic chemistry aims at reproducing structural and spectroscopic properties and ultimately the reactivity of metallic enzymes. In this context, our group has acquired a strong expertise in using simple and well-studied ligands covalently attached to a molecular cavity. We want now to follow another approach in which a coordination complex is fully embedded in a supramolecular capsule.

Internships for two master students on two different projects in the team of Christelle Hureau,  “Alzheimer et amyloïdes”, Laboratoire de Chimie de Coordination du CNRS. Dates are from January to June 2020 (5 to 6 months) paid about 570 Euros/month. A PhD position will be available in the team in 2020.

Starting no later than September 2, 2019. Within the framework of the European project Interreg Atlantic Area HYLANTIC, we are looking for a postdoctoral research associate responsible for the synthesis and characterization of organometallic catalysts for the photo-electrochemical production of hydrogen (H2).

Laboratory of chemistry and Biology of Metals (LCBM, Grenoble) Team : BioCE, Head : Dr S. Ménage Internaship supervisor : S. Ménage (DR CNRS) or C. Marchi-Delapierre (MCF HDR) ()

Laboratory: Bioenergetics and Protein Engineering (BIP), Aix-Marseille University & CNRS (France). Team: Biophysics of metalloproteins (Prof. B. Guigliarelli) Supervisor: Dr. Pierre Dorlet, HDR ()

Un poste de PU pour le Laboratoire des BioMolécules (LBM, laboratoire de Paris Centre, Sorbonne Université (SU)-ENS-CNRS) va être ouvert pour la campagne 2019 avec pour intitulé “Biologie chimique pour sonder le vivant”. Le recrutement concerne le pôle “Biomolécules: analyse et  interactions moléculaires et cellulaires” sur le site de Jussieu (SU).

ProtoMET. Protometabolic pathways: exploring the chemical roots of systems biology. Includes 9 months at University College London (UK), University of Strasbourg (France) and Metallopharm (USA). More information from

The eSCALED consortium, in collaboration with the Horizon 2020 Marie Sklodowska-Curie programme, is delighted to offer 14 Early Stage Researcher positions. The successful candidates will enrol in double PhD programs involving 2 partner universities, starting latest in October 2018, for ground-breaking research on Artificial Photosynthesis Devices.

The objective of the PhD Thesis is to develop and explore new molecular homogenous and heterogenous catalysts for the reduction of carbon dioxide and low-weight organic derivatives. The synthesized compounds will be characterized by various spectroscopic techniques. Special emphasis will be placed on the spectroelectrochemical characterization (IR, UV-Vis-NIR) of intermediates for full understanding of the mechanisms. Immobilization of the most promising molecular catalysts onto conductive support (electrode) will be also developed to perform heterogeneous catalysis.

l’INC du CNRS a attribué au Laboratoire d’Electrochimie Moléculaire – UMR 7591 (LEM) un poste d’assistant(e) ingénieur(e) (AI) en analyse chimique (BAP B), ouvert au concours externe en 2017, pour une prise de fonction au 01 décembre 2017. Le LEM est donc à la recherche d’un(e) candidat(e) pour ce type de poste.

Un poste d’Ingénieur Recherche (BAP C : Expert-e en développement d’expérimentation) sera ouvert au concours externe au mois de mai-juin 2017 à l’institut de chimie de l’université de Strasbourg au laboratoire POMAM (Propriétés Optiques et Magnétiques des Architectures Moléculaires)

A CEA-funded PhD position is available at the Laboratoire de Chimie des Métaux de Transition (UMR 5249, CEA-CNRS-Université Grenoble Alpes; Grenoble, France). The position will open in October 2017, in the SolHyCat group (www.solhycat.com), for a 3-year PhD research-project dedicated to the synthesis and study of bio-inspired metal-sulfides clusters for the activation of small molecules (N2, HCN, CO2).

Un poste d’ingénieur recherche “Responsable de la plate-forme de Résonance Paramagnétique Electronique” est ouvert dans le cadre de la mobilité interne au CNRS (poste NOEMI) jusqu’au 17 janvier à l’institut de chimie de Strasbourg dans le groupe de P. Turek. Pour plus d’informations cliquer vers le lien suivant: http://web-rh.dsi.cnrs.fr/afip/owa/!consult.liste_AFIP  

The Bioelectrochemistry and Vibrational Spectroscopy Group in chemistry department of the University of Strasbourg in France, offers a PhD position, to work on an exciting, multi-disciplinary project. The group has expertise in a variety of research areas including infrared / THz, Raman spectroscopy and electrochemistry applied on proteins.

A postdoctoral researcher position in the synthesis and evaluation of new catalysts for carbon dioxide (photo)electroreduction is available for 12 months with a starting date from October 2015 to March 2016, in the frame of a “PSL‐Chimie” Project (CATACARB) involving three partners: ENS (Prof. C. Policar), Chimie ParisTech (Dr. F. Bedioui) and Collège de France (Prof. M. Fontecave)

Projet de thèse pluriscidisciplinaire conjoint entre le laboratoire de Bioénergétique et Ingénierie des Protéines (BIP) (équipe de Christophe Léger) et l’Institut Universitaire des Systèmes Thermiques Industriels (IUSTI): «Conception d’une nouvelle génération de cellules électrochimiques pour l’étude des enzymes qui réduisent le CO2»

URGENT. Dans le cadre d’un projet financé par la fondation A*MIDEX nous recherchons un ou une biochimiste pour prendre en charge la production de plusieurs métalloenzymes (hydrogénases FeFe et NiFe, CO-dehydrogénase) et leur caractérisation, selon des méthodes mises au point au laboratoire.

A 18 months post-doctoral fellowship is available in the “Biocatalysis” team (lead by Dr S. Ollagnier de Choudens) of the LCBM that works on the reactivity of systems involved in the assembly of complex inorganic structures involving biochemists and biologists. The project is financed by the French “Agence Nationale de la Recherche” (ANR).