The project’s aim is to elaborate a luminescent Cu(II)-sensor, that is able to measure specifically labile/exchangeable Cu(II)-concentrations in biological systems, from simpler cell culture medium to the challenging blood plasma. Such a Cu(II)-sensor would be very useful as a tool to understand the Cu metabolism and might have applications for diagnosis of diseases with increased exchangeable Cu pool concentrations such as Wilson’s or Alzheimer’s disease. The project incolves a consortium with several collaborators from different disciplines, including group from the …

[Expired] Postdoc Position (2 years) in Bio/Medicinal Inorganic Chemistry in Strasbourg on “Luminescent Sensor to Detect the Labile Cu(II)-Pool, a Diagnostic Parameter for Wilson’s and Alzheimer’s diseasethe project” Read more »

Rébecca Leblay, from the group BiosCiences, iSm2, Marseille spent two weeks in the LCC in Toulouse. This project was supported by FrenchBIC. My PhD aims at studying the activity of LPMO (Lytic Polysaccharide MonoOxygenases) bioinspired synthetic complexes and their potential activity to valorize recalcitrant biomass. Besides, in Toulouse, peptide ligands with a structure inspired of the first coordination sphere of the LPMO active site have been synthetized. To compare the nature and mechanism of oxidation by synthetic/peptide complexes, enzymes and …

[Project supported by FrenchBIC] Études mécanistiques de complexes à cuivre bioinspirés par la LPMO Read more »

Dans cet épisode, présenté par Marc Hennebelle, en plus des chroniques de Titouan Chetot et de Maxime Ducreux, nous découvrons le monde passionnant de la chimie bio-inorganique et discutons des questions de parité dans les sciences. Lire aussi: Pourquoi si peu de femmes dans les carrières scientifiques ? de Clotilde Policar et Charlotte Jacquemot, dans The Conversation.