A postdoctoral position (expected starting date: autumn 2023) is available at the “Institut des Sciences Moléculaires de Marseille” (iSm2, UMR 7313) within the frame of an ANR-funded project. The laboratory is located in Saint-Jérôme campus of Aix-Marseille University.
Support is available for projects that span redox enzymes associated with CO2 reduction, heme peroxidases, AdoMet Radical Enzymes, and multi-heme cytochromes.
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This Ph.D. is financed by an ANR project (Bioinspired Oxidation of Methane). It will be pursued at the Institute of Molecular Sciences of Marseille, and will focus on the development of new caged catalysts based on Fe- or Cu- complexes. These structures will strongly enhance the catalytic efficiency of this challenging reaction, while keeping an excellent selectivity.
The aim of this project, emerged within the L2CM laboratory, is to develop a novel approach utilizing optical imaging to track the biotransformations of metal-based drug candidates in view of rationalizing their further pharmacomodulation. This will allow to establish a relationship between metal’s coordination sphere, metal-ligand interaction, and the complexes’ biotransformations to rationalize drug design. Web: http://www.l2cm.univ-lorraine.fr/l2cm/
Profil détaillé du poste : Etudes électrochimiques d’une nouvelle sous famille d’hydrogénases FeFe
