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FrenchBIC is a CNRS network of about 200 French researchers from 25 research units, who work on all aspects of bioinorganic chemistry / metals in biology

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Iron is essential for bacterial survival, but it is particularly difficult to access within the host, where it is tightly controlled and often scarce. To acquire this essential nutrient, the opportunistic pathogen Pseudomonas aeruginosa has an extensive arsenal of 21 transport systems located in its outer membrane. Many of these systems rely on siderophores, small molecules that bind iron with high affinity and allow bacteria to acquire it. However, P. aeruginosa does not express all of these systems simultaneously. Instead, …

[Journal Club] A study published by Isabelle Schalk and Gaëtan Mislin’s team (UMR7242, University of Strasbourg) reveals how Pseudomonas aeruginosa adapts its iron-acquisition strategy to its environment Read more »

Posted in Nouvelle équipe du GIS Tagged with Posted on

Our group, hosted by the Institut des Sciences Analytiques, focuses on the structural and dynamical characterization of intrinsically disordered and multi-domain proteins related to some important biological questions, namely, the bacterial silver resistance and schistosomiasis chronic parasitic disease.

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The I2BC is recruiting new team leaders. The institute offers a vibrant, multidisciplinary environment in Biochemistry/Biophysics/Structural Biology; Cell Biology; Genome Biology; Microbiology; and Virology. All teams benefit from state-of-the-art I2BC technological facilities in next-generation sequencing, proteomics, bio-imaging, biophysics, structural biology and integrative bioinformatics.

Posted in FrenchBIC, webinar Posted on

The aim of these webinars is to bring the community together around a series of 2 talks of 30+10 minutes, with a frequency of about once every two months. The webinars will be followed by an informal online meeting space.

Posted in Nouvelle équipe du GIS, FrenchBIC Tagged with Posted on

The Laboratory of Supramolecular Bioinorganic Chemistry at the Institut de Science et d’Ingénierie Supramoléculaires (ISIS), University of Strasbourg and CNRS, led by Irene Regeni develops biocompatible metal-based systems at the interface of supramolecular coordination chemistry and chemical biology.