This Ph.D. is financed by an ANR project (Bioinspired Oxidation of Methane). It will be pursued at the Institute of Molecular Sciences of Marseille, and will focus on the development of new caged catalysts based on Fe- or Cu- complexes. These structures will strongly enhance the catalytic efficiency of this challenging reaction, while keeping an excellent selectivity.

The aim of this project, emerged within the L2CM laboratory, is to develop a novel approach utilizing optical imaging to track the biotransformations of metal-based drug candidates in view of rationalizing their further pharmacomodulation. This will allow to establish a relationship between metal’s coordination sphere, metal-ligand interaction, and the complexes’ biotransformations to rationalize drug design. Web: http://www.l2cm.univ-lorraine.fr/l2cm/

“Chasing the Elusive “In-Between” State of the Copper-Amyloidβ Complex by X-ray Absorption through Partial Thermal Relaxation after Photoreduction”, published by the group of Peter Faller in Angew Chem Int Ed Engl . 2023 Mar 3;e202217791. doi: 10.1002/anie.202217791