The project aims to take advantage of the near-infrared (NIR) emission of lanthanide ions (LnIII) in an innovative multiplex imaging approach to establish an accurate map of SKCa channel subtypes and to correlate it with a disease prognosis and/or to optimize treatments. To achieve this goal, a series of imaging probes based on lanthanide(III)/gallium(III) metallacrowns exhibiting fingerprint bright emission in the NIR range and conjugated to peptides with controlled specificity for the SKCa family will be prepared.

Waiting for the next 13th international Biometals symposium, we decided, after discussion of several colleagues involved in the IBS society, to set up monthly webinars consisting of two keynote presentations. One of these will correspond possibly to an article or review recently published in the Biometals journal. After each talk there will be an open discussion.