Laboratory of Chemistry and Biology of Metals (LCBM), Grenoble. Computational chemistry, Modellig, and X-rays (CoMX) team. Expires on Sunday February 2nd, 2025
30 June 2025- 3 July 2025 Expires on Thursday July 3rd, 2025
Fluorescent probes for the detection and quantification of traces of copper(II) in biological fluids. The projects aims at designing peptide and lanthanide-based sensors to detect Cu(II) by fluorescence in biological fluids. We are looking for a motivated postdoc with skills in molecular chemistry.
The objective of this project is to develop novel bioinspired nanohybrid catalysts based on synthetic copper complexes fo ORR and OER. These complexes will be immobolized at Carbon-Nanotubes-based electrodes. The position is avalable as soon as possible
Two thesis prizes were awarded in 2024, to Afridi Zamader and Andrea Fasano.
A postdoctoral position in Structural Biology is available in the Metalloproteins group at IBS in Grenoble, France.
Financing: Labex Arcane (https://arcane.univ-grenoble-alpes.fr) Place of work: CEA/LCBM, Grenoble, France (https://www.cbm-lab.fr/en) Directors of thesis: Dr. Ragnar Bjornsson (CEA Grenoble), Dr. Christine Cavazza (CEA Grenoble) PhD starting date: October 2024
The project deals with the biosynthesis and the potential of new antimicrobial peptides from mammalian gut microbiomes in the context of the fight against antibiotic resistance
Interested in biological imaging with metal complexes? We are looking for a PhD in organic/bioorganic/inorganic chemistry to develop luminescent probes for cell and small animal imaging.
The 11th FrenchBIC online webinar will take place on Thursday April 4th at 10.30am, and it will be given by: Sarah Hostachy (SyMMES, CEA Grenoble), Chemical biology approaches to investigate metal-protein interactions: the case of f-elements (abstract); Ewen Bodio (ICMUB, Université de Bourgogne), Replacing boron atom by a metal ion in aza-BODIPY fluorophores: a new way to design innovative imaging probes (abstract). The format of the seminar is two 30+10 min talks, followed by a meeting time in an online …
C’est avec une grande tristesse que nous avons appris vendredi 9 juin la disparition d’Etienne Mulliez à l’âge de 73 ans.
The project, developed within two laboratories in Grenoble (DCM and LCBM), aims to develop efficient and selective catalysts for electro driven hydrogenation reactions of unsaturated C-O/C-N bonds using metal-pincer complexes and the integration of the latter into functional photo(electro)catalytic systems.
Copper-Based Molecular Electrocatalyst for Strong C-H bond Activation The project will be developed within two groups (BIOCEN and CIRe) in DCM possessing complementary recognized expertise in chemical design and synthesis, characterization techniques, molecular electrochemistry and in functionalization of carbon-based nanomaterials.
The eighth FrenchBIC online webinar will take place on Tuesday 17th of January at 10.30am, and it will be given by: Aurore Thibon-Pourret (DCM, Grenoble), Bio-inspired dicopper complexes: investigations of new relevant species in copper-based oxidation processes (abstract); Vincent Lebrun (Institut de Chimie de Strasbourg), Installing a LPMO-inspired copper binding site onto amyloid-like fibrils (abstract). The format of the seminar is two 30+10 min talks, followed by a meeting time in an online space for informal discussions. The seminar will …
We are looking for a research assistant (AI) for managing the chemistry labs of two research teams (CIRE and EMPRE, see the link) and the synthesis of organic molecules and coordination complexes. One year initial contract with possible extension.
“The contribution of structural biology to the understanding of the mechanism of metalloproteins” Friday, July 22nd 2022 at the IBS-GRENOBLE
to study the reactivity of metal-thiolate complexes towards molecular nitrogen and other N-containing small molecules
Synthesis of biomimetic copper complexes to understand the role of Met-rich domains in copper homeostasis.
ouvert à concours dans le laboratoire de Physiologie Cellulaire & Végétale à Grenoble (France) pour étudier la tolérance aux métaux chez les plantes. https://jobs.inrae.fr/concours/concours-charges-recherche-classe-normale-profil-h-f/cr-2022-bap-5
Carbazole-based luminescent lanthanide bioprobes for reactive oxygen species sensing in live cells
Le laboratoire de Chimie et Biologie des Métaux (LCBM UMR5249 CNRS/CEA/UGA) est à la recherche d’une chercheuse/chercheur post-doctoral.es pour un projet à l’interface Chimie/Biologie; en partenariat avec la start-up INNOVERDA dans le cadre du plan de relance.
Grenoble, from July 17 to 21, 2022.
Des chercheurs du groupe Métalloprotéines de l’institut de biologie structurale à Grenoble, de l’université UCDavis et de l’Illinois, aux États Unis, ont déterminé la structure cristalline d’un intermédiaire de maturation de l’hydrogénase à Fer.
Research in the Laboratory of Chemistry and Biology of Metals (CBM, Grenoble, France. https://www.cbm-lab.fr/en) focuses on the study of the structure, activity and regulation of complex biological systems that transport and use metal ions, and on the development of bio-inspired systems for applications in health, the environment and energy. The size of the Laboratory and the coherence of its research make it unique at both the national and international levels.
The pluri-disciplinary project, developed by a collaboration between two teams of the Lab BEE and BioCE, deals with in cristallo biocatalysis for a sustainable chemistry is still open. Our strategy for catalysis consists in the use of crystals of metalloenzymes to perform cascade reactions, that will impact the organic synthesis and the mode of drug synthesis.
An institute without a wall, the Institut des Métaux en Biologie (IMBG) is defined as a thematic research network, bringing together a large community of Grenoble researchers and teacher-researchers whose common point is a scientific project: Chemistry and Biology metals in living systems.
The pluri-disciplinary project, developed by a collaboration between two teams of the Lab BEE and BioCE, deals with in cristallo biocatalysis for a sustainable chemistry. Our strategy for catalysis consists in the use of crystals of metalloenzymes to perform cascade reactions.
L’équipe Métaux et Organes (Met&Or) s’intéresse à l’étude de l’homéostasie des métaux chez les mammifères dans des contextes tant physiologiques que pathologiques ainsi que dans le cas d’expositions environnementales aux métaux telles que les nanoparticules métalliques. Ces études nécessitent le développement de méthodologies innovantes notamment en imagerie mais également sur le plan des modèles de culture cellulaires. Nos thématiques principales concernent, le devenir des nanoparticules d’argent dans le foie, l’homéostasie du cuivre en conditions physiologiques et pathologiques, le développement de …
L’équipe Métaux et Organes (Met&Or) du LCBM à Grenoble rejoint le GIS Read more »
L’équipe “Bioénergie et environnement” s’intéresse à la bio-activation de petites molécules par des métalloenzymes et des micro-organismes anaérobies. Les thématiques sont centrées autour de l’étude du métabolisme énergétique de microorganismes capables de métaboliser des gaz (CO, CO2, CH4, H2). Les microorganismes modèles seront les deux bactéries photosynthétiques Rhobobacter capsultatus et Rhodospirillum rubrum et l’archée méthanogène Methanococcus maripaludis. La compréhension des mécanismes enzymatiques mis en jeu dans ces processus ainsi que l’optimisation de procédés catalytiques (à base d’enzymes naturelles ou artificielles) …
L’équipe “Bioénergie et environnement” du LCBM à Grenoble rejoint le GIS Read more »
At the Laboratory of Chemistry and Biology of Metals, CEA Grenoble. The goal is to implement bio-orthogonal chemistry in mammalian cells and apply it for the study of the copper chaperone Atox1 by different approaches such as super resolution fluorescence microscopy.
Notre collègue Serge Crouzy, chercheur CEA au Laboratoire Chimie et Biologie des Métaux de Grenoble (LCBM, UMR-5249) nous a quittés le 6 avril 2020, à l’âge de 57 ans.
Theoretical studies of Copper Centers to understand the reactivity of novel copper based catalysts capable of effectively oxidizing strong C-H bonds under mild and ecocompatible conditions and to study one of the key steps of the biosynthesis of melanins by tyrosinase, a binuclear copper enzyme.
Permanent contract with CEA at Grenoble – IRIG, SyMMES (UMR 5819 Univ. Grenoble Alpes, CEA, CNRS)
Department of Molecular Chemistry offers a full-time PhD Position (m/f) for a period of 3 years, starting in October 2020.
A doctoral position is available in the Metalloproteins Unit (MU) at the Institut de Biologie Structurale (IBS) in Grenoble – France to work on the structural study of the assembly machinery of the nitrogenase active site.
A background in molecular biology and protein biochemistry is essential, knowledge of macromolecular crystallography would be an advantage. Details and application at: https://esrf.gestmax.eu/1397/1/phd-position-structural-basis-of-melanogenesis-enzymes/en_US
Investigation of the peculiar nickel-binding site of the metalloprotein CooT by hyperpolarized solid-state NMR
July 6 – 10. You are invited to attend the 12th International BioMetals Web Symposium (BioMetals 2020), organized by Dr. Isabelle Michaud-Soret (chair) from the Biosciences and Biotechnologies Institute of Grenoble.
Implementation of noble metal-free catalytic nanomaterials in water splitting electrolyzers
Advanced course: September 22nd-24th, 2019 Conference: September 24th-27th, 2019 Villard-de-Lans, France
Beginning September-October 2019
Du 26 au 29 Septembre 2019, Grenoble
KeyWords: Artificial metalloenzyme – heterogeneous catalysis
KeyWords: artificial metalloenzyme – G quadruplex – catalysis
July 17-21th, 2022, Grenoble, France.
Spectroscopy and theoretical chemistry: complementary approaches for bio-inspired inorganic chemistry. From 25 to 30 November 2018 at the Escandille centre in Autrans (Isère)
Protein‐Based Nanotechnologies for the development of biosensors and bio‐batteries
10-14 September 2018, Grenoble, France
Place of work: BIG, CEA-Grenoble, Rhône-Alpes, France Salary: ~2000-2200 € / month
September 10-14th, 2018, Grenoble.
Mimer la photosynthèse des plantes pour convertir, grâce à la lumière, des molécules stables et abondantes comme l’eau et le CO2 en carburant hautement énergétique (l’hydrogène) ou en produits chimiques d’intérêt pour l’industrie, est aujourd’hui un défi majeur de la recherche.
Development of ultrastable fluorescent proteins markers for quantitative super resolution microscopy at cryogenic temperature.
![[Expired] 14 Marie Skłodowska ‐ Curie Positions for Early Stage Researchers in the Field of Artificial Photosynthesis](https://i0.wp.com/frenchbic.cnrs.fr/wp-content/uploads/2018/04/logo.jpg?fit=1332%2C624&ssl=1){kind=logo}
The eSCALED consortium, in collaboration with the Horizon 2020 Marie Sklodowska-Curie programme, is delighted to offer 14 Early Stage Researcher positions. The successful candidates will enrol in double PhD programs involving 2 partner universities, starting latest in October 2018, for ground-breaking research on Artificial Photosynthesis Devices.
A 3 year funded position is available at the département de chimie moléculaire (DCM, UMR 5250)-Univ. Grenoble-Alpes-France.
A CEA-funded PhD position is available at the Laboratoire de Chimie et Biologie des Métaux (UMR 5249, Univ. Grenoble Alpes-CNRS-CEA; Grenoble, France).
Au printemps 2017, le GIS a attribué 8 bourses à des doctorant·e·s et post-doctorant·e·s de nos équipes pour participer à la réunion jointe FrenchBIC/ISABC. Voici (au fil de l’eau) les comptes-rendus suite à leurs retours de mission.
Synthesis and application for charge photoaccumulation of novel ruthenium photosensitizers featuring poly-N-heterocyclic ligands as electron storage sites
Synthetic peptides as mimics of DCLK2, a Map Protein involved in neural repair
… to characterize reactive intermediates formed in a hydrogen-evolving photocatalytic system combining a novel ruthenium photosensitizer and a cobalt catalyst by EPR spectroscopy.
An ANR-funded PhD position is available at the Département de chimie moléculaire de Grenoble (UMR 5250, Université Grenoble-alpes/CNRS). This 3-year funded PhD position is dedicaced to copper and zinc complexes for recognition of phospholipids.
A CEA-funded PhD position is available at the Laboratoire de Chimie des Métaux de Transition (UMR 5249, CEA-CNRS-Université Grenoble Alpes; Grenoble, France). The position will open in October 2017, in the SolHyCat group (www.solhycat.com), for a 3-year PhD research-project dedicated to the synthesis and study of bio-inspired metal-sulfides clusters for the activation of small molecules (N2, HCN, CO2).
![[Expired] Several postdoctoral positions in coordination chemistry / bioinorganic chemistry at the university Grenoble-Alpes](https://i0.wp.com/frenchbic.cnrs.fr/wp-content/uploads/2016/06/arcane.png?fit=324%2C110&ssl=1)
Three 2-year postdoctoral positions in chemistry are available at Grenoble. These projects concern the development of molecular catalysts for multi-electron reduction of small earth-abundant molecules (H+, CO2, N2), and are funded by LaBEX Arcane & ANR.
![[Expired] 2ème Colloque “Solar Fuels” / Journée Nationale des Carburants Solaires](https://i0.wp.com/frenchbic.cnrs.fr/wp-content/uploads/2016/05/gdr-solar-fuels.jpg?fit=250%2C115&ssl=1)
Escandille – Autrans (Vercors), du 29 mai au 1er juin 2017.
En mars 2016, le GIS a attribué 9 bourses à des doctorant·e·s et post-doctorant·e·s de nos équipes. Voici (au fil de l’eau) les comptes-rendus suite à leurs retours de mission.
September 13th-15th 2017, Villard-de-Lans
![[Expired] Journées de Chimie de Coordination de la Société Chimique de France](https://i0.wp.com/frenchbic.cnrs.fr/wp-content/uploads/2016/10/version_4.png?fit=978%2C162&ssl=1)
JCC 2017 – 26 et 27 Janvier 2017 – Grenoble
L’utilisation de nouvelles sources d’énergie propres représente un objectif majeur pour nos sociétés modernes dont les besoins en énergie augmentent constamment. La mise au point de procédés pour la production d’hydrogène via des ressources renouvelables tels que l’eau ou l’énergie solaire représente une solution séduisante.
![[Expired] Two-year post-doctoral position: new functional hybrid materials for asymmetric photocatalytic oxygenation](https://i0.wp.com/frenchbic.cnrs.fr/wp-content/uploads/2016/02/cea-1.jpg?fit=180%2C181&ssl=1)
Laboratoire de Chimie et Biologie des Métaux-UMR 5249 Grenoble, France
L’équipe Biosystèmes Electrochimiques et Analytiques fait partie du Département de Chimie Moléculaire de Grenoble. Une partie de ses thématiques concerne la synthèse et la caractérisation de complexes bio-inspirées de métalloenzymes, et une autre partie est liée à la fonctionnalisation d’électrodes par des métalloenzymes (hydrogénases, cuproenzymes, etc). L’équipe sera représentée au GIS par Alan Le Goff, que nous avons vu au cours de notre dernière réunion à Murol.
Deciphering the biosynthetic pathway of carbon monoxide dehydrogenase, a key enzyme of the water-gas shift reaction.
Design and synthesis of bio-inspired copper catalyst. One-year post doctoral position avilable in Grenoble (DCM, Université Grenoble Alpes)
A 2-year postdoctoral position in chemistry is available at the “Département de Chimie Moléculaire” of Grenoble. The project is about “Calixarene Molybdenum based (electro)catalysts for ammonia production under mild conditions”.
CRYSTALBALL – Artificial enzymes as heterogeneous catalysts
Chemistry & Biology of Iron Sulfur Cluster 13th-18th september 2015, Villars de Lans A Two-Day Advanced Course (13-15 Sept.), Conference (16-18 Sept.)
A 18 months post-doctoral fellowship is available in the “Biocatalysis” team (lead by Dr S. Ollagnier de Choudens) of the LCBM that works on the reactivity of systems involved in the assembly of complex inorganic structures involving biochemists and biologists. The project is financed by the French “Agence Nationale de la Recherche” (ANR).
Ecoconception et écotoxicité de nouveaux agents biocides à base de nanoparticules d’argent à enrobages bioinspirés
Development of new eco-aware photocatalysts for tandem oxygenation reactions.
Une école thématique, co-organisée par le CNRS et le Labex grenoblois Arcane, aura lieu en juin prochain : « Surf’Ing’Chem’2015 »
Grenoble (Autrans) du 31 Mai au 04 Juin 2015.
L’attribution de la bourse internationale m’a permis d’assister au congrès “XXIV tRNA conference” (http://www.trna2012.cl/), du 2 au 6 décembre 2012, à Olmué, Chili.
22-26 juillet 2013, Grenoble, France. http://www.icbic16.com ICBIC est un congrès international qui a lieu tous les deux ans et regroupe environ 900 scientifiques du monde entier. Il sera organisé pour la première fois en France en Juillet 2013, à Grenoble.
The Institute of Metals in Biology of Grenoble (IMBG) organizes in September 2012 its 5th biannual International Meeting that will be dedicated to “Metal Homeostasis”, a topic already chosen in 2004 for the inaugural edition of this series of meetings.