This Ph.D. is financed by an ANR project (Bioinspired Oxidation of Methane). It will be pursued at the Institute of Molecular Sciences of Marseille, and will focus on the development of new caged catalysts based on Fe- or Cu- complexes. These structures will strongly enhance the catalytic efficiency of this challenging reaction, while keeping an excellent selectivity.

The aim of this project, emerged within the L2CM laboratory, is to develop a novel approach utilizing optical imaging to track the biotransformations of metal-based drug candidates in view of rationalizing their further pharmacomodulation. This will allow to establish a relationship between metal’s coordination sphere, metal-ligand interaction, and the complexes’ biotransformations to rationalize drug design. Web: http://www.l2cm.univ-lorraine.fr/l2cm/

Join LEM to develop catalytic systems for electrocatalytic oxidation of various organic substrates, using O2 and earth abundant metal complexes. You will thoroughly study the catalytic activities of selected Fe an Mn complexes and quantify and optimize their performances (efficiency and selectivity) using complementary synthetic, spectroscopic and electrochemical tools.

 Join us in determining the mechanisms of catalysis by metalloenzymes through the development and implementation of electron-nuclear double resonance (ENDOR) spectroscopy: The ENDOR and DFT characterization of key trapped catalytic and photogenerated intermediates  reveals mechanism, with synthetic biomimetic complexes providing key constraints!