The project aims to take advantage of the near-infrared (NIR) emission of lanthanide ions (LnIII) in an innovative multiplex imaging approach to establish an accurate map of SKCa channel subtypes and to correlate it with a disease prognosis and/or to optimize treatments. To achieve this goal, a series of imaging probes based on lanthanide(III)/gallium(III) metallacrowns exhibiting fingerprint bright emission in the NIR range and conjugated to peptides with controlled specificity for the SKCa family will be prepared. Expires on Monday …

[Job] 6 months M2 training at the Centre de Biophysique Moléculaire in Orléans : Synthesis and characterization of lanthanide-based metallacrowns for near-infrared biological imaging Read more »

The seventh FrenchBIC online webinar will take place on October Wednesday 19th at 10.30am, and it will be given by: Svetlana Eliseeva (CBM, Orléans), Lanthanide(III)/gallium(III) and lanthanide(III)/zinc(II) metallacrowns for near-infrared luminescence and photoacoustic imaging (abstract); Benoît Bertrand (Sorbonne Université), Biphenyl-gold(III) scaffold: a new field of investigations for anticancer drug candidates (abstract). The format of the seminar is two 30+10 min talks, followed by a meeting time in an online space for informal discussions. The seminar will be given online, there: …

FrenchBIC online webinar – October 2022 Read more »